as harjo said we can't really do that, at least not in the client itself because then you are always to late.
To disable a bit more "caching" you could change on the admin page 2 properties:
servoy.clientJarLoadOption:
servoy.fastClientStartup:
make sure the first one is on "eager" and the second one is on "false"
If you want to do more, then give your users a batch file that they have to click on and you delete in that batch file all the stuff that you want (or modify everything you want)